Sclerosing adenosis (SA) is a benign proliferative condition of the terminal duct lobular units characterised by an increased number of acini and their glands. English Translation, Synonyms, Definitions and Usage Examples of Spanish Word ‘adenosis esclerosante mamaria’. el diagnóstico diferencial de lesiones benignas que simulan carcinoma, tales como hiperplasia cribiforme, adenosis esclerosante e hiperplasia adenomatosa .

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Sclerosing Polycystic Adenosis of the Submandibular Gland | Acta Otorrinolaringológica Española

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There are few cases of SPA that have esclerosanet multinodular. The most common site of presentation of a salivary neoplasm is the parotid gland. These tumors are diagnosed at a mean age of 40 years and the mean tumor size is in the range of 0. Therefore, we must always consider this entity when conducting the differential diagnosis, since, while still remaining a neoplasm, treatment and prognosis of this disease are different from those of other malignant tumours of the salivary glands.

Sclerosing adenosis can appear as a focal or diffuse lesion. Support Radiopaedia and see fewer ads. The treatment consists in excision of the tumor with a superficial parotidectomy, which has demonstrated high cure rates.

This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment. Breast – nonmalignant Adenosis Adenosis of breast – general Author: Sclerosing polycystic adenosis SPA is a rare entity which was first described in Normal glands in upper right.


It is characterised by a slow growth, which is usually asymptomatic, nodular and similar in many respects to esclreosante breast disease.

Retention of myoepithalial type cells but loss of ductal epithelium. It mainly affects the major salivary glands, especially the parotid gland, although it may exceptionally affect the minor salivary glands.

A woman of 22 years old with no pathologic family history has a negative IgM, but with a positive IgG Epstein-Barr serum antibody test.

Pathology Outlines – Sclerosing adenosis

January – February Pages Hed Neck Pathol, 2 adehosis, pp. Sclerosis polycyst adenosis of the parotid gland. Many women with sclerosing adenosis experience recurring pain that tends to be linked to the menstrual cycle.

Furthermore, immunohistochemistry techniques have detected positivity for oestrogen and progesterone receptors which may play a role in its pathogenesis.

Adenosis of the Breast

When is a diagnosis of sclerosing adenosis acceptable at core biopsy? A cervical computed tomography CT scan revealed a solid nodule of 16 mm in the left submandibular gland, with an adenopathy of 6 mm adjacent to the submaxillary gland. Unable to process the form.

Right to privacy and informed consent. Given these findings, we performed a left submaxillectomy with neck dissection of group I. The provisional probable diagnosis was a parotid tumor with a clinical and radiological benign behavior, likely a pleomorphic adenoma.

At one year of follow-up, the patient is asymptomatic, with a favorable clinical outcome and without tumor relapse.

The aetiology of this condition is currently unknown, although some recent articles have reported conducting trials with human androgen-receptor gene HUMARA6 and demonstrated its clonal esclerosxnte, therefore, neoplastic nature. Clonal nature of sclerosing polycystic adenosis of salivary glands demonstrated by using the polymorphism of the human androgen receptor HUMARA locus as a marker.


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All cases of SPA have been unilateral like this case esdlerosante. Proliferation of acini and ducts, some of them dilated, in a sclerotic stroma with a slight, chronic, inflammatory infiltrate. There are few diagnosed cases by fine needle cytology, in which cases there are found syncytial cells of epithelial ducts with apocrine changes. Initially, it was asymptomatic and subsequently the patient developed light dysesthesias in the region.

SPA is considered a disease due to a pseudotumoral inflammatory reaction. Introduction The parotid gland tumors are classified according to their morphological and histological patterns. It is important to carry out the differential diagnosis with other salivary gland tumours, mainly acinar cell carcinoma. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.

Adenosis of breast – general. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. The patient was a smoker. Page views in