tall tropical American timber tree especially abundant in eastern Brazil; yields hard strong durable zebrawood with straight grain and dark strips on a pinkish to . Gonçalo Alves ou Gonçaleiro (Astronium fraxinifolium) Família Anacardiaceae. Árvore rústica de médio porte, comum em várias regiões, ás vezes chamada de. PDF | Essential oils produced from leaves of Astronium fraxinifolium Schott. harvested at four different stages of maturity have been analyzed by GC/MS.

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Line drawing of the flowering branch Photograph by: Additionally, we decided to use the gold hamster model to evaluate the activity of our plant materials in vivo based on the fact that hamsters are known to be highly susceptible to Leishmania subgenus Viannia infection [ 35 ].

The data relating to the parasite load were analyzed using the nonparametric Mann-Whitney test. View at Google Scholar E. Several studies have been published confirming much of the popular use of Plectranthus amboinicussuch as anti-inflammatory and antimicrobial activities [ 23 — 27 ]. No inflammation was found in the uninfected animals treated with the plant material. View at Google Scholar F. Another problem is related to the lower efficacy of the drugs in children compared to adults [ 11 ].

The treatment started when the lesions appeared 3 weeks. The Myracrodruon urundeuva species, a plant of the same family, native in northeastern Brazil, is widely used in folk medicine for treatment of various dermatological disorders and is known to have antimicrobial [ 19 ], antiulcer [ 20 ], and anti-inflammatory activities [ 21 ].

Astronium graveolens brasiliensis Engl. The profiles of lesion thickness were similar to the standard treatment. Further, golden hamsters were infected s.

Astronium fraxinifolium – Useful Tropical Plants

If frxinifolium would like to support this site, please consider Donating. The lesion sizes from treated and untreated animals were analysed by the one-way Anova and complemented by the Tukey-Kramer test for multiple comparisons.


A superb work, with the minor irritation that the translation from Portuguese is not of the best. The strain of L.

Astronium fraxinifolium Images

Sierra Romero, and Z. Now containing plants. Leishmania amazonensisand L. Early diagnosis and treatment are important to prevent sequelae. Statistical Analysis The data relating to the parasite load were analyzed using the nonparametric Mann-Whitney test. It is fraxinifoljum used in the treatment of various diseases including skin, digestive tracts, urogenital, respiratory disorders, infections, and pain [ 22 ].

The treatment was initiated when the lesions appeared about the 20th day after infection. In conclusion, in vivo studies showed a high efficacy when the infected animals were intralesionally treated with leaf ethanolic extract from A.

The animals showed a significant reduction of lesion thickness in the 6th week, but it was not comparable to the animals treated with Glucantime. The analyses were performed using GraphPad Prism version 5.

The animals were injected subcutaneously in right hind footpad with 10 astroniumm stationary phase L. The treatment was initiated when the lesions appeared about the 27th day.

Various factors contribute to fraxinidolium increase of the disease incidence, for instance, the process of urbanization which alters the environment in decurrence of economic and social pressures [ 5 ]. The arrow indicates start of treatment about the 27th day.

In general, these compounds are also expensive and require long-term treatment [ 8 ]. Not for the casual reader.

Publisher Weinheim Year ISBN – Description An excellent and very comprehensive guide but it only gives very short descriptions of the uses without any details of how to utilize the plants. Cytotoxicity of the plant material. The second protocol consisted of 15 daily intralesional injections. Indexed in Science Citation Index Expanded.

The aim of the present work was to evaluate antileishmanial activity of Astronium fraxinifolium and Plectranthus amboinicus. The supernatant was discarded, and the cells were resuspended fraxinifoliuk culture medium. For each experiment, cells were removed from the culture medium and incubated with 0. One hundred microliters of these dilutions was distributed into well flat bottom plates containing agar-blood in 6 replicates per concentration.


HIV-positive individuals are probably at high risk of developing cutaneous leishmaniasis [ 9 ] probably at more severe forms of the disease.

In Vitro Studies 2. Miltefosine and fluconazole have recently showed effectiveness showed effectiveness against CL [ 1415 ], but despite their lower toxicity, these second line drugs are not useful against other forms of leishmaniasis [ 13 ]. For the test treatment, two protocols were used.

View at Google Scholar O. After the 7th week of infection, the lesion thickness in the group treated with the plant material was below the limit of normal thickness.

To receive news and publication updates for BioMed Research International, enter your email vraxinifolium in the box below. Increased incidence of resistance to the drug has been described [ 8 ]. Its activities are poorly known unlike astroniu, other plant from the same family, M. According to their data, mice infected with L. The animals were treated with leaf ethanolic extract from Astronium draxinifolium EEF.

Lesion thickness a and number of parasites b in hamster footpad infected with 10 6 promastigotes of Leishmania braziliensis. As it was shown in our previous study [ 26 ], the major component in asronium oil obtained from P. Introduction Leishmaniasis is a disease that affects human beings and animals and is caused by the protozoa parasite of the genus Leishmania which is transmitted by the bite of infected female phlebotomine sandflies and displays a spectrum of manifestations which goes frwxinifolium cutaneous involvement CL with late destruction of mucous membranes to generalized systemic visceral disease VL with fatal outcome if not treated [ 1 ].

The uninfected contralateral footpad was also intralesionally injected with the same solution used for treatment.