Holothoria atra, is a holothurian of order Aspidochirotes belonging to the family Description a Sea Cucumber Species Holothuria atra Jaeger, from. Native range | All suitable habitat | Point map | Year This map was computer-generated and has not yet been reviewed. Holothuria atra AquaMaps Data. Holothuria (Holothuria) atra Jaeger, AphiaID. (urn:lsid: :taxname). Classification. Biota; Animalia.

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Please review our privacy policy. Triterpene glycosides, namely holothurinosides A, B, C and D as well as desholothurin A from sea cucumber Holothuria forskalihave considerable antitumour activity against P cell lines. A new immunomodulatory lead Cumaside a complex of monosulfated triterpene glycosides from the sea cucumber Cucumaria japonica possesses cytotoxic activity against Ehrlich carcinoma cells Aminin et al.

The extract LPS obtained from Stichopus japonicus induced inflammatory response via blocks the MAPK signaling pathway in murine macrophages, showed in vitro with anti-inflammatory potential Himayaa et al. It could be predicted that high molecular weight compounds present in Holothuria atra detected by NMR analysis could form a potent antiviral sources Additional file 1.

In other projects Wikimedia Commons Wikispecies. A total of 59 natural compounds were identified from the extracts of sea cucumber H. Structurally, these glycosides exhibit a moderate cytotoxicity against human leukemia cell lines Prassas and Diamandis Considering these as well as the results of present investigations, the methanolic extracts of Holothuria hlothuria could form effective antitumour and antiviral agents.

Cytotoxic effects of H. The name, molecular weight holothuuria the components was ascertained. Table 3 Percentage cell inhibition and characterization of cell line exposed to Holothuria atra using tryphan blue. The authors are grateful and thankful to Dr. Holothuria atra Conservation status.


Spectra was obtained in the EI mode with 70eV ionization energy. From NMR analysis the structural elucidation of the active compounds were studied. Intercedenside D—I iso lated a cytotoxic triterpene glycoside from the sea cucumber Mensamaria intercedens a marine natural product inhibited proliferation of several human cancer cell lines Zou et al.

DID holoturia out the studies on antitumor and antiviral activities using the H. James suggests that great potential exists for the extraction of valuable bioactive compounds from the sea cucumbers in the Indian coast. Implications for selfoligomerization and haemolytic processes. C15H24 24 2,poxy-5,8-hectadecadienol C17H30O2 It was placed in the subgenus Halodeima by Pearson inmaking its full scientific name Holothuria Halodeima atra.

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The mechanism by which they block tumor growth is driven by the inhibition of receptor tyrosine kinases RTKs that are over expressed by cancer cells Chi Am J Clin Path. Class — sea cucumbers, Holothuroidea; order — Holothugia family — holothuriids, Holothuriidae.

Each experiment was conducted as triplicates sets. In low concentrations, the extract showed potent inhibitory effect towards Herpes simplex virus and thus has got significant drug value.

Some holothurians from Guam and vicinity.

The species is fished in uolothuria parts of its range, but the processed product is of low commercial value. Aaron Premnath Lipton, Email: It is the type species of the subgenus.

Holothuria atra

Articles from SpringerPlus are provided here courtesy of Springer-Verlag. Similarly the inhibitory effects of Herpes simplex virus 1 and 2 cells were detected using the plaque reduction assay. All authors read and approved the final manuscript. The 13C NMR spectrum showed the presence of a carbon—carb on double and indicated the presence of two conjugated carbonyls. Antibacterial activity was determined using Muller Hinton agar Hi Media.


Cytotoxic and antifungal triterpene glycosides from the Patagonian sea cucumber Hemoiedema spectabilis. Author information Article notes Copyright and License information Disclaimer. The anus is at the other end. The sea cucumber Telenata ananas derived bioactive compounds were reported to act as the chemokine receptor subtype-5 CCR5 with possible anti-HIV activity Hegde et al.

It is not possible to distinguish between male and female Holothuria atra externally.

Prior to incubation, an overlay medium comprising of 0. Eur J Org Chem. You can continue searching for Holothuria atra on one of these Web sites: The active fractions obtained from column chromatography were analysed for Nuclear magnetic resonance spectroscopy NMR analysis.

This article has been cited by other articles in PMC. This article is published under license to BioMed Central Ltd. Previous work showed that sulphated polysaccharides such as glycosaminoglycans an inhibitor of human immunodeficiency virus binds to T lymphocytes and showed antiviral activity Toido et al. The Black Sea Cucumber, the most commonly encountered holothurian in Qatar, is an omnivore feeder, sifting through the sediment with its tentacles and feeding on detritus and other organic matter while at the same time ingesting sand grains.

Antitumor activity was measured by holotjuria the IC 50 values.