JURANYI ZSOLT PDF

Jurányi Zsolt is the author of Az alvilág zsoldjában ( avg rating, 16 ratings, 1 review, published ) and Az alvilág csapdájában ( avg rating. nov. Az alvilág csapdájában has 3 ratings and 1 review. Sándor said: Az első rész fényévekkel jobb volt, szerintem. Csak azért vergődtem végig. List of computer science publications by Zsolt Jurányi.

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When risperidone and Org were added in combination, a decrease in extracellular dopamine concentrations was accompanied with sustained elevation of extracellular glycine levels.

Risperidone increased extracellular concentrations of dopamine but failed to influence those of glycine or glutamate measured in microdialysis samples. Our data indicate that coadministration of an antipsychotic with a GlyT-1 inhibitor may normalize hypofunctional NMDA receptor-mediated glutamatergic neurotransmission with reduced dopaminergic side effects characteristic for antipsychotic medication.

Combined drug administration with D2 dopamine receptor blockade and activation of hypofunctional NMDA receptors may be needed for a more effective treatment of positive and negative symptoms and the accompanied cognitive deficit in schizophrenia. T1 – Alterations in brain extracellular dopamine and glycine levels following combined administration of the glycine transporter type-1 inhibitor Org and risperidone.

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Loop | Zsolt Juranyi

Abstract The most dominant hypotheses for the pathogenesis of schizophrenia have focused primarily upon hyperfunctional dopaminergic and hypofunctional glutamatergic neurotransmission in the central nervous system. Neurochemical Research35 12 Combined drug administration with D 2 dopamine receptor blockade and activation of hypofunctional NMDA receptors may be needed for a more effective treatment of positive and negative symptoms and the accompanied cognitive deficit in schizophrenia.

The most dominant hypotheses for the pathogenesis of schizophrenia have focused primarily upon hyperfunctional dopaminergic and hypofunctional glutamatergic neurotransmission in the central nervous system. The therapeutic efficacy of all atypical antipsychotics is explained in part by antagonism of the dopaminergic neurotransmission, mainly by blockade of D2 dopamine receptors.

The therapeutic efficacy of all atypical antipsychotics is explained in part by antagonism of the dopaminergic neurotransmission, mainly by blockade of D 2 dopamine receptors.

Interestingly, the extracellular concentrations of glutamate were also zsokt. Keywords Antipsychotic agents Extracellular glycine and dopamine Glycine transporter type-1 inhibitors Microdialysis Schizophrenia. To investigate this type of combined drug administration, rats were treated with the atypical antipsychotic risperidone together with the GlyT-1 inhibitor Org Link to publication in Scopus.

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Neurochemical ResearchVol. AB – The most dominant hypotheses for the pathogenesis of schizophrenia have focused primarily upon hyperfunctional dopaminergic and hypofunctional glutamatergic neurotransmission in the central nervous system.

Alterations in brain extracellular dopamine and glycine levels following combined administration of the glycine transporter type-1 inhibitor Org and risperidone.

dblp: Zsolt Jurányi

Link to citation list in Scopus. N-methyl-d-aspartate NMDA receptor hypofunction in schizophrenia can be reversed by glycine transporter type-1 GlyT-1 inhibitors, which regulate glycine juuranyi at the vicinity of NMDA receptors.

N2 – The most dominant hypotheses for the pathogenesis of schizophrenia have focused primarily upon hyperfunctional dopaminergic and hypofunctional glutamatergic neurotransmission in the central nervous system. Org injection reduced extracellular dopamine concentrations and elevated extracellular glycine levels but the concentrations of serine and glutamate were not changed.

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